Plasma S-Adenosylmethionine Is Associated with Lung Injury in COVID-19.
Evgeny Vladimirovich KryukovAlexander Vladimirovich IvanovVladimir Olegovich KarpovValery Vasil'evich AleksandrinAlexander Mikhaylovich DygaiMaria Petrovna KruglovaGennady Ivanovich KostiuchenkoSergei Petrovich KazakovAslan Amirkhanovich KubatievPublished in: Disease markers (2021)
A high SAM level and high methylation index are associated with the risk of lung injury in patients with COVID-19. The association of SAM with IL-6 and glutathione indicates an important role of transmethylation in the development of cytokine imbalance and oxidative stress in patients with COVID-19.