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Unraveling the regulation of mTORC2 using logical modeling.

Kirsten ThobeChristine SersHeike Siebert
Published in: Cell communication and signaling : CCS (2017)
The results and additional data suggest that more than one regulator is necessary to explain the behavior of mTORC2. Finally, this study proposes a new experiment to validate mTORC1 as second essential regulator.
Keyphrases
  • transcription factor
  • electronic health record
  • machine learning