Mineral-Enhanced Polyacrylic Acid Hydrogel as an Oyster-Inspired Organic-Inorganic Hybrid Adhesive.
Ang LiYunfei JiaShengtong SunYisheng XuBurcu Baykal MinskyM A Cohen StuartHelmut CölfenRegine von KlitzingXuhong GuoPublished in: ACS applied materials & interfaces (2018)
Underwater adhesion is crucial to many marine life forms living a sedentary lifestyle. Amongst them, mussel adhesion has been mostly studied, which inspires numerous investigations of 3,4-dihydroxyphenylalanine (DOPA)-based organic adhesives. In contrast, reef-building oysters represent another important "inorganic" strategy of marine molluscs for adhesion by generating biomineralized organic-inorganic adhesives, which is still rarely studied and no synthetic analogues have ever been reported so far. Here, a novel type of oyster-inspired organic-inorganic adhesive based on a biomineralized polyelectrolyte hydrogel is reported, which consists of polyacrylic acid physically cross-linked by very small amorphous calcium carbonate nanoparticles (<3 nm). The mineral-enhanced polyelectrolyte hydrogel adhesive is shown to be injectable, reusable, and optically clear upon curing in air. Moreover, comparable adhesion performance to DOPA-based adhesives is found for the hydrogel adhesive in both dry and wet conditions, which can even be further enhanced by introducing a small amount of second large cross-linker such as negatively charged nanoparticles. The present mineral hydrogel represents a new type of bio-inspired organic-inorganic adhesive that may find a variety of potential applications in adhesive chemistry.
Keyphrases
- water soluble
- drug delivery
- hyaluronic acid
- tissue engineering
- wound healing
- biofilm formation
- physical activity
- magnetic resonance
- cardiovascular disease
- perovskite solar cells
- type diabetes
- pseudomonas aeruginosa
- magnetic resonance imaging
- molecular docking
- staphylococcus aureus
- escherichia coli
- molecular dynamics simulations