Pretreatment with P2Y12 inhibitors in ST-elevation myocardial infarction: A systematic review and meta-analysis.
Douglas Mesadri GewehrPedro Emanuel de Paula CarvalhoCaroline Serafim DagostinRhanderson CardosoTaiane Belinati Loureiro KubruslyFernando Bermudez KubruslyLuis Fernando KubruslyPublished in: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions (2023)
Our analysis suggests that pretreatment with oral P2Y12 inhibitors before PCI in patients with STEMI was not associated with reduced all-cause mortality, myocardial infarction, or major bleeding. However, pretreatment with P2Y12 inhibitors in the pre-hospital setting appears to be beneficial in reducing reinfarction.