Single-cell expression profile of Drosophila ovarian follicle stem cells illuminates spatial differentiation in the germarium.

Zhi DongLan PangZhiguo LiuYifeng ShengXiaoping LiXavier ThibaultAmy ReileinDaniel KalderonJianhua Huang

Published in: BMC biology (2023)

Our data establishes an important resource of scRNA-seq profiles for FSCs and their immediate derivatives that is based on precise spatial location and functionally established stem cell identity, and facilitates future genetic investigation of regulatory interactions guiding FSC behavior.

Keyphrases

stem cells
single cell
rna seq
genome wide
high throughput
cell therapy
transcription factor
current status
dna methylation
big data
gene expression
machine learning
copy number
deep learning
data analysis