Mitochondrial energetics in skeletal muscle are associated with leg power and cardiorespiratory fitness in the Study of Muscle, Mobility, and Aging (SOMMA).
Theresa MauLi-Yung LuiGiovanna DistefanoPhilip A KramerSofhia V RamosFrederico G S ToledoAdam J SantanastoEric G ShanklandDavid J MarcinekMichael J JurczakIan SipulaFiona M BelloKate A DuchownyAnthony J A MolinaLauren M SparksBret H GoodpasterRussell T HeppleStephen B KritchevskyAnne B NewmanPeggy M CawthonSteven R CummingsPaul M CoenPublished in: The journals of gerontology. Series A, Biological sciences and medical sciences (2022)
Higher muscle mitochondrial energetics measures were associated with both better cardiorespiratory fitness and greater leg power in older adults. Muscle mitochondrial energetics explained a greater degree of variance in VO2 peak compared to leg power.