Genetic predisposition to smoking is associated with risk of rheumatoid arthritis: a Mendelian randomization study.

Yu QianLingzhi ZhangDavid J H WuZhijun XieChengping WenYingying Mao

Published in: Arthritis research & therapy (2020)

These results provide support for a causal association between smoking and increased risk of RA. Further studies are warranted to explain the underlying mechanisms of smoking in the development of RA.

Keyphrases

rheumatoid arthritis
smoking cessation
disease activity
ankylosing spondylitis
interstitial lung disease
genome wide
systemic lupus erythematosus
gene expression
copy number