Genetic profiles of transcriptomic clusters of childhood asthma determine specific severe subtype.

Y-L YehM-W SuB-L ChiangYao-Hsu YangC-H TsaiYungling Leo Lee

Published in: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology (2018)

Gene expression profiling of PBMC is useful for the identification of TH 1/TH 17-mediated asthma with poor treatment control. PBMC and CD8+ T cells could be important targets for the investigation and identification of severe asthma.

Keyphrases

gene expression
chronic obstructive pulmonary disease
lung function
single cell
allergic rhinitis
bioinformatics analysis
dna methylation
early onset
genome wide
air pollution
combination therapy
young adults
replacement therapy