A cross-sectional study evidences regulations of leukocytes in the colostrum of mothers with obesity.

Raúl Piñeiro-SalvadorEduardo Vazquez-GarzaJosé Antonio Cruz-CardenasCuauhtémoc Licona-CassaniGerardo García-RivasJorge Moreno-VásquezMario René Alcorta-GarcíaVictor Javier Lara-DiazMarion E G Brunck

Published in: BMC medicine (2022)

This is the first characterization of major leukocyte subsets in colostrum of mothers suffering from obesity and the first report of colostrum leukocyte subpopulations in Latin America. We evidence various significant alterations of most leukocyte populations between blood and colostrum and demonstrate a decreased colostrum B lymphocyte fraction in obesity. This pioneering study is a stepping stone to further investigate active immunity in human breastmilk.

Keyphrases

peripheral blood
human milk
insulin resistance
metabolic syndrome
weight loss
high fat diet induced
type diabetes
weight gain
low birth weight
endothelial cells
physical activity
adipose tissue
preterm infants
induced pluripotent stem cells