Differences in Age-related Retinal and Cortical Atrophy Rates in Multiple Sclerosis.
Christian CordanoBardia NourbakhshHao H YiuNico PapinuttoEduardo CaverzasiAhmed AbdelhakFrederike Cosima OertelAlexandra Beaudry-RichardAdam SantanielloSimone SaccoDaniel J BennettApraham GomezChristina J SigurdsonStephen L HauserRoberta MagliozziBruce Anthony Campbell CreeRoland G HenryAri J GreenPublished in: Neurology (2022)
An age-dependent reduction in retinal and cortical volume loss rates during relapsing-remitting MS suggests deceleration in neurodegeneration in the earlier period of disease and further indicates that the period of greatest adaptive immune-mediated inflammatory activity is also the period with the greatest neuroaxonal loss.