Infusion of autologous bone marrow derived mononuclear stem cells potentially reduces urinary markers in diabetic nephropathy.
Abduzhappar E GaipovZhannat TaubaldiyevaManarbek AskarovZaiyrkhan TurebekovLarisa KozinaAskhat MyngbayOlga UlyanovaSaltanat TuganbekovaPublished in: Journal of nephrology (2018)
Infusion of autologous bone marrow-derived mononuclear cells significantly reduced levels of MAU in DN patients. Further studies with larger sample size are needed to confirm these observations.
Keyphrases
- diabetic nephropathy
- stem cells
- end stage renal disease
- cell therapy
- low dose
- bone marrow
- newly diagnosed
- ejection fraction
- mesenchymal stem cells
- peripheral blood
- chronic kidney disease
- induced apoptosis
- peritoneal dialysis
- prognostic factors
- cell cycle arrest
- patient reported outcomes
- oxidative stress
- cell death
- cell proliferation
- signaling pathway
- case control