Safety and efficacy of tight versus loose glycemic control in acute stroke patients: A meta-analysis of randomized controlled trials.
Shuangzhe WuYuke MaoSijia ChenPeiyan PanHuiying ZhangSiqi ChenJue LiuDong-Hua MiPublished in: International journal of stroke : official journal of the International Stroke Society (2024)
There was no difference between tight and loose glycemic control on mortality, independence, or recurrent stroke outcome in acute stroke, but an increase in hypoglycemia. There was a small effect improvement on neurological scales, but the relevance of this needs to be confirmed in future adequately powered studies.
Keyphrases
- glycemic control
- type diabetes
- blood brain barrier
- blood glucose
- liver failure
- weight loss
- cerebral ischemia
- atrial fibrillation
- insulin resistance
- systematic review
- respiratory failure
- cardiovascular events
- current status
- drug induced
- aortic dissection
- case control
- metabolic syndrome
- adipose tissue
- skeletal muscle
- acute respiratory distress syndrome
- extracorporeal membrane oxygenation
- subarachnoid hemorrhage