Induction of endoplasmic reticulum stress is associated with the anti-tumor activity of monepantel across cancer types.

Tiffany J HarrisYang LiaoWei ShiMarco EvangelistaBhupinder PalHamsa PuthalakathRoger AstonRichard MollardJohn M MariadasonErinna F LeeWalter Douglas Fairlie
Published in: Cancer medicine (2023)
As these outcomes are all associated with mTOR signalling, cell cycle and autophagy, we now provide a likely triggering mechanism for the anti-cancer activity of monepantel.