Blood-Brain Barrier Permeability Is Associated With Cognitive Functioning in Normal Aging and Neurodegenerative Diseases.
Danielle C HergertOwen GaasedelenSephira G RymanJillian PrestopnikArvind CaprihanGary A RosenbergPublished in: Journal of the American Heart Association (2024)
The study provides empirical support for a vascular contribution to white matter injury and cognitive impairment, directly or indirectly via BBB permeability. This highlights the importance of targeting modifiable vascular risk factors to help mitigate future cognitive decline.