Viral Determinants of Acute COVID-19 Symptoms in a Nonhospitalized Adult Population in the Pre-Omicron Era.

Sarah A GoldbergScott LuMiguel Garcia-KnightMichelle C DavidsonMichel TassettoKhamal AnglinJesus Pineda-RamirezJessica Y ChenPaulina R RugartSujata MathurCarrie A FormanKevin C DonohueGlen R AbediSharon SaydahMelissa Briggs-HagenClaire M MidgleyRaul AndinoMichael J PelusoDavid V GliddenJeffrey N MartinJ Daniel Kelly

Published in: Open forum infectious diseases (2023)

We found evidence to support the association of viral RNA load and infectious virus on some, but not all symptoms. Fever was most strongly associated with the presence of infectious virus; this may support the potential for symptom-based isolation guidance for COVID-19.

Keyphrases

sars cov
coronavirus disease
respiratory syndrome coronavirus
liver failure
sleep quality
respiratory failure
drug induced
aortic dissection
hepatitis b virus
patient reported
depressive symptoms
extracorporeal membrane oxygenation