Effects of caffeine on ethanol-elicited place preference, place aversion and ERK phosphorylation in CD-1 mice.
Simona PorruRiccardo MaccioniValentina BassareoAlessandra T PeanaJohn D SalamoneMercè CorreaElio AcquasPublished in: Journal of psychopharmacology (Oxford, England) (2020)
The present data indicate a functional antagonistic action of caffeine and ethanol on associative learning and extracellular signal-regulated kinase phosphorylation after an acute interaction. These results could provide exciting grounds for further studies, also in a translational perspective, of their pharmacological interaction modulating other processes involved in drug consumption and addiction.
Keyphrases
- protein kinase
- signaling pathway
- liver failure
- drug induced
- cell proliferation
- respiratory failure
- electronic health record
- high fat diet induced
- transcription factor
- big data
- emergency department
- type diabetes
- tyrosine kinase
- metabolic syndrome
- aortic dissection
- intensive care unit
- hepatitis b virus
- insulin resistance
- adipose tissue