Possible effect of OAS1 and TMPRSS6 but not DPP4 and ZNF335 polymorphisms on COVID-19 severity in the Czech population.

Jaroslav A HubáčekTom PhilippVěra AdámkováOndřej MájekDana DlouháLadislav Dušek

Published in: Central European journal of public health (2024)

Common variants within OAS1 (rs4767027) and TMPRSS6 (rs855791) play some role in COVID-19 pathology in the Czech Caucasian population. Whether the depletion of minor allele carriers of these two variants is associated with increased COVID-19 mortality, needs to be analysed in an external confirmatory study.

Keyphrases

coronavirus disease
sars cov
copy number
respiratory syndrome coronavirus
cardiovascular events
gene expression
risk factors
type diabetes
coronary artery disease
african american
genome wide