Curcumin attenuates lupus nephritis by inhibiting neutrophil migration via PI3K/AKT/NF-κB signalling pathway.

Hui YangHaiwei ZhangLili TianPanpan GuoShanshan LiuHongwei ChenLingyun Sun

Published in: Lupus science & medicine (2024)

Curcumin significantly inhibits the recruitment of neutrophils and the release of proinflammatory factors in the kidney by inhibiting the PI3K/AKT/NF-κB signalling pathway, providing new therapeutic targets and medication strategies for the treatment of LN.

Keyphrases

signaling pathway
pi k akt
cell cycle arrest
cell proliferation
healthcare
emergency department
combination therapy
toll like receptor
immune response
replacement therapy