Strategic Stereoselective Halogen (F, Cl) Insertion: A Tool to Enhance Supramolecular Properties in Polyols.

To improve the supramolecular properties of organic compounds, chemists continuously need to identify new tools. Herein, the influence of the stereoselective insertion of halogen atoms (F or Cl) on different supramolecular properties is analyzed. Inserting anti-halohydrins in polyols considerably strengthens the H-bonding networks and other supramolecular interactions. This behavior resulted in improved anion binding, H-bonding catalysis, or organogel properties of the designed polyols with strong perspectives for applications in other classes of substrates.