Clinicopathological impacts of DNA methylation alterations on pancreatic ductal adenocarcinoma: prediction of early recurrence based on genome-wide DNA methylation profiling.
Yutaka EndoMao FujimotoNanako ItoYoriko TakahashiMinoru KitagoMasahiro GotohNobuyoshi HiraokaTeruhiko YoshidaYuko KitagawaYae KanaiEri AraiPublished in: Journal of cancer research and clinical oncology (2021)
These findings indicate that DNA methylation alterations may have a clinicopathological impact on PDAC. Application of our criteria will ultimately allow prediction of ER after surgery to improve the outcome of PDAC patients.