The Role of Sirtuin 1 in Palmitic Acid-Induced Endoplasmic Reticulum Stress in Cardiac Myoblasts.

Hsiang-Yu Yang Jhao-Ying ChenYen-Nien HuoPei-Ling YuPei-Zhen LinShih-Che Hsu Shih-Ming HuangChien-Sung TsaiChih-Yuan Lin

Published in: Life (Basel, Switzerland) (2022)

concentration is diminished by PA-induced ER stress, leading to decreased Sirt1 activity. The Sirt1 activator SRT1720 promotes the nuclear translocation of ATF4 in PA-treated H9c2 cells.

Keyphrases

endoplasmic reticulum stress
induced apoptosis
oxidative stress
diabetic rats
ischemia reperfusion injury
high glucose
left ventricular
nuclear factor
heart failure
cell cycle arrest
endothelial cells
cell proliferation
atrial fibrillation
immune response