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[Associations between the oxytocinergic system genes, perinatal complications and interpersonal relationships in patients with schizophrenia].

V A MikhailovaT V LezheikoN Yu KolesinaV E Golimbet
Published in: Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova (2021)
The results are in accordance with the notions accepted on the basis of numerous evidences that link the genes of the oxytocinergic system with social behavior. We obtained new data on the influence of the known polymorphism OXTR rs53576 on the phenotype, which has not been studied previously in this aspect - the ability to form interpersonal relationships in patients with schizophrenia, while it was shown that the effect of the genotype depends on the environmental risk factor (perinatal complications).
Keyphrases
  • risk factors
  • genome wide
  • pregnant women
  • bioinformatics analysis
  • genome wide identification
  • healthcare
  • mental health
  • electronic health record
  • dna methylation
  • big data