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N(Omega)-nitro-l-arginine methyl ester potentiates lidocaine analgesic and anaesthetic effect in rats.

An-Kuo ChouYu-Wen Chen
Published in: The Journal of pharmacy and pharmacology (2022)
L-NAME at 60 nmol (the minimum effective dose) increases and prolongs the effect of cutaneous analgesia of lidocaine. L-NANE at an ineffective dose potentiates lidocaine analgesic and anaesthetic effects.
Keyphrases
  • neuropathic pain
  • anti inflammatory
  • nitric oxide
  • pain management
  • ultrasound guided
  • spinal cord injury
  • amino acid