Delineating the role of single-nucleotide polymorphism of CYP19 gene on aromatase activity in South Indian women with polycystic ovary syndrome.
Pravesh HegdeShilpa S ShettyPrasanna Kumar ShettyLakshmi ManjeeraD Prashanth ShettySuchetha Kumari NPublished in: Journal, genetic engineering & biotechnology (2023)
CYP19 rs2414096 polymorphism was not associated with PCOS; however, the homozygous wild GG genotype may exhibit reduced aromatase activity with subsequent hyperandrogenism implicating endocrine abnormalities.