Histological validation of atrial structural remodelling in patients with atrial fibrillation.
Yuya TakahashiTakanori YamaguchiToyokazu OtsuboKana NakashimaKodai ShinzatoRyosuke OsakoShigeki ShichidaYuki KawanoAkira FukuiAtsushi KawaguchiShinichi AishimaTsunenori SaitoNaohiko TakahashiKoichi NodePublished in: European heart journal (2023)
Histological correlates of atrial structural remodelling were fibrosis, increased intercellular space, myofibrillar loss, and decreased nuclear density. Each histological component was defined using electron microscopy and immunohistochemistry studies.