[Cell loss in retinal ischemia is associated with increased necroptosis].
Teresa TsaiLeonie DeppeH Burkhard DickStephanie Christine JoachimPublished in: Die Ophthalmologie (2024)
Necroptotic processes appear to be activated 7 days after ischemia reperfusion, contributing to retinal cell death and activation of astrocytes. Late autophagic processes are not activated 7 days after ischemia. Necroptosis-associated parameters could therefore be targeted as an early therapeutic approach after ischemia in the future.