Avoiding the pitfalls of gene set enrichment analysis with SetRank.

Cedric SimillionRobin LiechtiHeidi E L LischerVassilios IoannidisRemy Bruggmann

Published in: BMC bioinformatics (2017)

The benchmarking results show that SetRank is a highly specific tool for GSEA. Furthermore, we show that the reliability of results can be improved by taking sample source bias into account. SetRank is available as an R package and through an online web interface.

Keyphrases

genome wide
copy number
gene expression