Pharmacotherapy for the treatment of depression in patients with alzheimer's disease: a treatment-resistant depressive disorder.

Madia LozuponeMaddalena La MontagnaFrancesca D'UrsoCarla PiccininniRodolfo SardoneVittorio DibelloGianluigi GiannelliVincenzo SolfrizziAntonio GrecoAntonio DanieleNicola QuarantaDavide SeripaAntonello BellomoGiancarlo Logroscino Francesco Panza

Published in: Expert opinion on pharmacotherapy (2018)

The present RCT methodologies are too disparate to draw firm conclusions. Future studies are required to identify effective and multimodal pharmacological treatments that efficiently treat depression in AD. Genotyping may boost antidepressant treatment success.

Keyphrases

depressive symptoms
major depressive disorder
bipolar disorder
dna methylation
pain management
combination therapy
physical activity
cognitive decline
current status
chronic pain
genome wide
replacement therapy
stress induced