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MALDI-IMS as a Tool to Determine the Myocardial Response to Syndecan-2-Selected Mesenchymal Stromal Cell Application in an Experimental Model of Diabetic Cardiomyopathy.

Kathleen PappritzOliver KleinFengquan DongNazha HamdaniArpad KovacsLisa O'FlynnSteve EllimanTimothy O'BrienCarsten TschöpeSophie Van Linthout
Published in: Proteomics. Clinical applications (2020)
IMS enables the characterization of differences in titin intensity distribution following MSC application. However, further analysis of titin phosphorylation is needed to allow for the assessment of the therapeutic efficacy of MSC.
Keyphrases
  • bone marrow
  • mass spectrometry
  • single cell
  • type diabetes
  • heart failure
  • left ventricular
  • cell therapy
  • high intensity
  • wound healing
  • protein kinase
  • atrial fibrillation