Evaluating whole genome sequence data from the Genetic Absence Epilepsy Rat from Strasbourg and its related non-epileptic strain.
Pablo Miguel Casillas-EspinosaKim L PowellMingfu ZhuC Ryan CampbellJessica M MaiaZhong RenNigel C JonesTerence J O'BrienSlavé PetrovskiPublished in: PloS one (2017)
This study highlights an approach for using whole genome sequencing to narrow down to a manageable candidate list of genetic variants in a complex genetic epilepsy animal model, and suggests utility of this sequencing design to investigate other spontaneously occurring animal models of human disease.