Occasional cannabis use is associated with higher premorbid functioning and IQ in youth at clinical high-risk (CHR) for psychosis: Parallel findings to psychosis cohorts.
L KennedyB S KuJ AddingtonC M AmirC E BeardenT D CannonR CarriónB CornblattM KeshavanD PerkinsD MathalonW StoneE WalkerS WoodsK S CadenheadPublished in: Schizophrenia research (2024)
Better premorbid functioning positively predicts both better social functioning and higher IQ which in turn is associated with a moderate cannabis use pattern in CHR, similar to reports in first-episode and chronic psychosis samples. Better premorbid functioning likely represents a protective factor in the CHR population and predicts a better functional outcome.