Novel Intraoperative Navigation Using Ultra-High-Resolution CT in Robot-Assisted Partial Nephrectomy.
Kiyoshi TakaharaYoshiharu OhnoKosuke FukayaRyo MatsukiyoTakuhisa NukayaMasashi TakenakaKenji ZennamiManabu IchinoNaohiko FukamiHitomi SasakiMamoru KusakaHiroshi ToyamaMakoto SumitomoRyoichi ShirokiPublished in: Cancers (2022)
To assess the perioperative and short-term functional outcomes of robot-assisted partial nephrectomy (RAPN) with intraoperative navigation using an ultra-high-resolution computed tomography (UHR-CT) scanner, we retrospectively analyzed 323 patients who underwent RAPN using an UHR-CT or area-detector CT (ADCT). Perioperative outcomes and the postoperative preservation ratio of estimated glomerular filtration rate (eGFR) were compared. After the propensity score matching, we evaluated 99 patients in each group. Although the median warm ischemia time (WIT) was less than 25 min in both groups, it was significantly shorter in the UHR-CT group than in the ADCT group (15 min vs. 17 min, p = 0.032). Moreover, the estimated blood loss (EBL) was significantly lower in the UHR-CT group than in the ADCT group (33 mL vs. 50 mL, p = 0.028). However, there were no significant intergroup differences in the postoperative preservation ratio of eGFR at 3 or 6 months of follow-up (ADCT 91.8% vs. UHR-CT 93.5%, p = 0.195; and ADCT 91.7% vs. UHR-CT 94.0%, p = 0.160, respectively). Although no differences in short-term renal function were observed in intraoperative navigation for RAPN in this propensity score-matched cohort, this study is the first to demonstrate that UHR-CT resulted in a shorter WIT and lower EBL than ADCT.
Keyphrases
- image quality
- computed tomography
- dual energy
- contrast enhanced
- high resolution
- robot assisted
- positron emission tomography
- patients undergoing
- end stage renal disease
- magnetic resonance imaging
- small cell lung cancer
- newly diagnosed
- chronic kidney disease
- type diabetes
- ejection fraction
- magnetic resonance
- minimally invasive
- peritoneal dialysis
- epidermal growth factor receptor
- insulin resistance