Elevated Retinol Binding Protein 3 Concentrations Are Associated With Decreased Vitreous Inflammatory Cytokines, VEGF, and Progression of Diabetic Retinopathy.

Ward FickweilerHyunseok ParkKyoungmin ParkMargalit G MitznerTanvi ChokshiTahani BoumennaJohn GautierYumi ZaitsuI-Hsien WuJerry CavalleranoLloyd P AielloJennifer K SunGeorge Liang King

Published in: Diabetes care (2022)

Higher vitreous RBP3 concentrations are associated with less severe DR and slower rates of progression to PDR, supporting its potential as a biomarker and therapeutic agent for preventing DR worsening, possibly by lowering retinal VEGF and inflammatory cytokines.

Keyphrases

diabetic retinopathy
optical coherence tomography
binding protein
vascular endothelial growth factor
endothelial cells
editorial comment
drug induced