The cerebellar cognitive affective syndrome scale reveals early neuropsychological deficits in SCA3 patients.
Roderick P P W M MaasSven KillaarsBart P C van de WarrenburgDennis J L G SchutterPublished in: Journal of neurology (2021)
Essentially all SCA3 patients exhibited some form of cognitive impairment. The CCAS-S differentiates SCA3 patients from healthy controls, detects neuropsychological deficits early in the disease course, and correlates with relevant ataxia severity measures.