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Clear cell sarcoma: state-of-the art and perspectives.

Laureline WetterwaldNicolò RiggiAnastasios KyriazoglouGiovanni Dei TosAngelo Dei TosAntonia Digklia
Published in: Expert review of anticancer therapy (2023)
The current treatment strategy of advanced CCSs, based on STSs regimens, shows a lack of effective options. Combination therapies, in particular the association of immunotherapy and TKIs, represent a promising approach. Translational studies are needed in order to decipher the regulatory mechanisms involved in the oncogenesis of this ultra-rare sarcoma and identify potential molecular targets.
Keyphrases
  • clear cell
  • transcription factor
  • high resolution
  • case control
  • risk assessment
  • climate change