Multi-panel assay of serum autoantibodies in colorectal cancer.

Mitsunori UshigomeYoshihiro NabeyaHiroaki SodaNobuhiro TakiguchiAkiko KuwajimaMasatoshi TagawaKazuyuki MatsushitaJunichi KoikeKimihiko FunahashiHideaki Shimada

Published in: International journal of clinical oncology (2018)

The measurement of set of 17 autoantibodies allowed autoantibody profiling in patients with colorectal cancer. The combination assay of six tumor antigens (p53, RalA, HSP70, Galectin1, KM-HN-1, and NY-ESO-1) achieved a positive rate of 56%. Such high positive rates will be helpful for detecting colorectal cancer regardless of tumor stages.

Keyphrases

systemic lupus erythematosus
high throughput
heat shock protein
single cell
dendritic cells
heat stress
immune response