Association between the L55M and Q192R polymorphisms of the paraoxonase-1 gene and age-related macular degeneration: a meta-analysis.
Rebeca G Elguezabal-RodeloRenata Ochoa-PrecomaLeonardo M PorchiaRicardo Perez-FuentesMartha Elba Gonzalez-MejiaPublished in: Arquivos brasileiros de oftalmologia (2021)
The paraoxonase-1L55M polymorphism increases the risk of developing age-related macular degeneration in non-Asian populations, whereas in Asian populations, the polymorphism exerts a protective effect. However, for the paraoxonase-1 Q192R polymorphism, only the Asian population demonstrated a risk of developing age-related macular degeneration.