Non-invasive imaging of functional pancreatic islet beta-cell mass in people with type 1 diabetes mellitus.

Shruti S JoshiTrisha SinghLucy E KershawFraser W GibbMarc R DweckMichelle WilliamsIskandar IdrisScott SempleShareen ForbesDavid E NewbyRebecca M Reynolds

Published in: Diabetic medicine : a journal of the British Diabetic Association (2023)

Manganese-enhanced magnetic resonance imaging provides a potential reproducible non-invasive measure of functional beta-cell mass in people with type 1 diabetes mellitus. This holds major promise for the investigating type 1 diabetes, monitoring disease progression and assessing novel immunomodulatory interventions.

Keyphrases

type diabetes
magnetic resonance imaging
single cell
high resolution
cardiovascular disease
physical activity
metabolic syndrome
big data
machine learning
artificial intelligence
mass spectrometry
photodynamic therapy
bone marrow
magnetic resonance
adipose tissue
weight loss