The Imbalance of FOXP3/GATA3 in Regulatory T Cells from the Peripheral Blood of Asthmatic Patients.
Tiantian ChenXiaoxia HouYingmeng NiWei DuHuize HanYouchao YuGuochao ShiPublished in: Journal of immunology research (2018)
Treg cells decreased in asthmatic patients, with an impaired immunosupression function and a Th2-like phenotype, which may be due to overexpression of GATA3 and FOXP3, regulated by USP21 and PIM2, respectively.
Keyphrases
- regulatory t cells
- dendritic cells
- peripheral blood
- transcription factor
- end stage renal disease
- ejection fraction
- chronic kidney disease
- induced apoptosis
- newly diagnosed
- lung function
- cell proliferation
- cell cycle arrest
- peritoneal dialysis
- immune response
- cystic fibrosis
- chronic obstructive pulmonary disease
- patient reported