Differentiation between rebound thymic hyperplasia and thymic relapse after chemotherapy in pediatric Hodgkin lymphoma.
Friedrich Christian FrankeAdrian DamekJonas SteglichLars KurchDirk HasencleverThomas W GeorgiWalther Alexander WohlgemuthChristine Mauz-KörholzDieter KörholzRegine KlugeJudith Landman-ParkerWilliam Hamish WallaceAlexander FossåDirk VordermarkJonas KarlenAna Fernández-TeijeiroCepelova MichaelaTomasz KlekawkaAndishe AttarbaschiFrancesco CeppiAndrea HraskovaAnne UyttebroeckAuke BeishuizenKarin DieckmannThierry LeblancMartin MoellersBoris BuerkeDietrich StoevesandtPublished in: Pediatric blood & cancer (2023)
Isolated thymic LR is very uncommon. CHL relapse should be suspected when increasing tumor masses are present in distant sites outside of the thymic area. Conversely, if regrowth of lymphoma in other sites can be excluded, isolated thymic mass after CTX likely represents RTH.