Overall survival, disease-free survival and quality of life in patients affected by HPV mediated p16+ oropharyngeal squamous cell carcinoma treated with upfront trans-oral robotic surgery vs radiotherapy or chemoradiotherapy.
Giacomo FiacchiniMiriana PicarielloIacopo DallanDomenico TricòAugusto Pietro CasaniFederica AmatoFabiola PaiarStefano UrsinoStefano BerrettiniLuca BruschiniPublished in: European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery (2024)
For p16 + OPSCC PSG I patients, upfront surgery can be considered a valid alternative to radiotherapy or chemoradiotherapy while maintaining a comparable DFS and OS and giving patients better results in terms of specific aspects of their QoL.
Keyphrases
- squamous cell carcinoma
- end stage renal disease
- newly diagnosed
- ejection fraction
- locally advanced
- free survival
- prognostic factors
- radiation therapy
- peritoneal dialysis
- rectal cancer
- patient reported outcomes
- coronary artery disease
- percutaneous coronary intervention
- radiation induced
- atrial fibrillation
- acute coronary syndrome
- lymph node metastasis