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Baseline gut microbiota as a predictive marker for the efficacy of neoadjuvant chemotherapy in patients with early breast cancer: a multicenter prospective cohort study in the Setouchi Breast Project-14.

Shogo NakamotoYukiko KajiwaraKohei TaniguchiAkira I HidaYuichiro MiyoshiTakanori KinMari YamamotoDaisuke TakabatakeShinichiro KuboHajime HikinoYutaka OgasawaraMasahiko IkedaHiroyoshi DoiharaTadahiko ShienNaruto TairaTakayuki IwamotoShinichi Toyooka
Published in: Breast cancer research and treatment (2024)
Three species in the gut microbiota had potential associations with neoadjuvant chemotherapy efficacy, but the diversity of the gut microbiota was not associated with response to chemotherapy. Further research is needed to validate our findings.
Keyphrases
  • neoadjuvant chemotherapy
  • locally advanced
  • early breast cancer
  • lymph node
  • sentinel lymph node
  • rectal cancer
  • squamous cell carcinoma
  • radiation therapy
  • quality improvement
  • human health
  • early stage
  • genetic diversity