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No relevant midbrain atrophy in Parkinson's disease.

Elina M MyllerJ JoutsaJ IsotaloV Kaasinen
Published in: Acta neurologica Scandinavica (2016)
Mild midbrain atrophy is present in PD and can be detected with MRI. However, the midbrain atrophy in PD is not associated with the level of striatal dopaminergic dysfunction, and midbrain measurements therefore cannot be used as a clinically useful predictor of dopamine function.
Keyphrases
  • magnetic resonance imaging
  • oxidative stress
  • contrast enhanced
  • functional connectivity
  • uric acid
  • metabolic syndrome
  • diffusion weighted imaging