CYP2C19*2 Polymorphism Is Associated with Impaired Oral Clearance of Gliclazide in Healthy Chinese.
Elaine Y K ChowEmily Wm PoonBenny Sp FokJuliana Chung Ngor ChanChristopher Wai Kei LamPublished in: Pharmacogenomics and personalized medicine (2019)
CYP2C19*2 polymorphism is associated with increased total gliclazide concentration and reduced oral clearance. Pharmacogenetic studies are warranted on the impact of CYP2C19 polymorphisms on treatment response and hypoglycaemia.
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