Perioperative chemotherapy versus neoadjuvant chemoradiotherapy for esophageal or GEJ adenocarcinoma: A propensity score-matched analysis comparing toxicity, pathologic outcome, and survival.

Lucas GoensePieter C van der SluisPeter S N van RossumSylvia van der HorstGert J MeijerNadia Haj MohammadMarco van VulpenStella MookJelle P RuurdaRichard van Hillegersberg

Published in: Journal of surgical oncology (2017)

Compared to perioperative chemotherapy, neoadjuvant chemoradiotherapy achieves higher pathologic response rates and a lower risk of locoregional disease progression, without improving survival.

Keyphrases

locally advanced
rectal cancer
neoadjuvant chemotherapy
squamous cell carcinoma
radiation therapy
cardiac surgery
patients undergoing
free survival
oxidative stress
lymph node