Chromosomal microarray vs. NIPS: analysis of 5541 low-risk pregnancies.

Sagi-Dain LenaLital Cohen VigSarit KahanaShiri YacobsonTamar TenneIfat Agmon-FishmanCochava KleinReut MatarLina Basel-SalmonIdit Maya

Published in: Genetics in medicine : official journal of the American College of Medical Genetics (2019)

Clinically significant CMA aberrations are detected in 1 of 71 pregnancies with normal ultrasound, and in 1 of 131 women with no indication for invasive testing. Thus, CMA might be recommended a first-tier test in pregnancies with normal ultrasound.

Keyphrases

preterm birth
gestational age
magnetic resonance imaging
pregnancy outcomes
copy number
ultrasound guided
contrast enhanced ultrasound
computed tomography
pregnant women
genome wide