The miR-1224-5p/ELF3 Axis Regulates Malignant Behaviors of Pancreatic Cancer via PI3K/AKT/Notch Signaling Pathways.

Lingming KongPeng LiuMingjun ZhengZhongpeng WangYang GaoKeke LiangHuaitao WangXiaodong Tan

Published in: OncoTargets and therapy (2020)

The miR-1224-5p/ELF3 axis may serve as a new diagnostic, therapeutic, and prognostic biomarker in pancreatic cancer. The related PI3K/AKT/Notch/EMT signaling pathways greatly promote the elucidation of the progression of pancreatic cancer.

Keyphrases

pi k akt
signaling pathway
cell proliferation
cell cycle arrest
epithelial mesenchymal transition
induced apoptosis
cell death
oxidative stress