[Lung pathology in post-covid syndrome].
S N BugrovI V DvorakovskayaB M ArielPublished in: Arkhiv patologii (2023)
The clinic and pathological anatomy of the infection caused by the SARS-CoV-2 virus (coronavirus infection - CI) with the development of Post-Covid syndrome (PS) have not been studied enough. This also applies to morphofunctional changes in the lungs, one of the most important components of PS. We conducted a histological and bacterioscopic study of lung biopsy specimens in 20 patients of both sexes aged 22-75 years. In many patients, PS developed relatively late - not earlier than 1 year - 1 year 4 months after the onset of acute clinical symptoms of CI. Structural changes in the lungs in PS appear as an inflammatory reaction such as interstitial pneumonia. Most patients had nonspecific interstitial pneumonia with elements of organizing interstitial pneumonia, in some cases complicated by the presence of a specific granulomatous reaction, characteristic of pulmonary tuberculosis. Despite this, according to the results of traditional bacterioscopic and bacteriological studies, the tuberculous etiology of pulmonary fibrosis has not yet been confirmed. Perhaps this is due to the fact that we are talking about an inapparent tuberculosis infection, the causative agent of which is the L-form of Mycobacterium tuberculosis. Patients with PS who have pulmonary fibrosis on x-ray should be under the special supervision of a phthisiatrician or pulmonologist.
Keyphrases
- sars cov
- mycobacterium tuberculosis
- end stage renal disease
- pulmonary tuberculosis
- ejection fraction
- newly diagnosed
- prognostic factors
- peritoneal dialysis
- coronavirus disease
- rheumatoid arthritis
- patient reported outcomes
- oxidative stress
- respiratory failure
- computed tomography
- intensive care unit
- hepatitis c virus
- ultrasound guided
- extracorporeal membrane oxygenation
- case report
- acute respiratory distress syndrome
- fine needle aspiration
- idiopathic pulmonary fibrosis