Does Neoadjuvant Chemotherapy in Clinical T1-T2 N0 Triple-Negative Breast Cancer Increase the Extent of Axillary Surgery?
Chandler S CortinaJan Irene LlorenChristine RogersMorgan K JohnsonAdrienne N CobbChiang-Ching HuangAmanda L KongPuneet SinghMediget TeshomePublished in: Annals of surgical oncology (2024)
Patients who underwent upfront surgery were more likely to be pN+; however, ALND rates were similar between the two cohorts. Thus, the use of NAC does not result in a higher odds of ALND and the decision for NAC should be individualized and based on modern guidelines and systemic therapy benefits.
Keyphrases
- neoadjuvant chemotherapy
- minimally invasive
- lymph node
- coronary artery bypass
- sentinel lymph node
- transcription factor
- end stage renal disease
- locally advanced
- ejection fraction
- newly diagnosed
- stem cells
- peritoneal dialysis
- surgical site infection
- prognostic factors
- early stage
- radiation therapy
- patient reported outcomes
- decision making
- bone marrow
- genome wide analysis
- smoking cessation