Effect of Metabolite Levels on Type 2 Diabetes Mellitus and Glycemic Traits: A Mendelian Randomization Study.

Yue SunYa-Ke LuHao-Yu GaoYu-Xiang Yan

Published in: The Journal of clinical endocrinology and metabolism (2021)

Our findings suggest that AA and 2-HBA may have causal associations on T2DM and glycemic traits. This is beneficial for clarifying the pathogenesis of T2DM, which would be valuable for early identification and prevention for T2DM.

Keyphrases

glycemic control
type diabetes
genome wide
weight loss
insulin resistance
dna methylation
gene expression
metabolic syndrome
cardiovascular risk factors